Description
A continuation of BMS 5021 Molecular Basis of Medicine II, this course incorporates a problem based learning (PBL) approach to investigative fundamental biomedical concepts within the context of clinical cases. The objective of the course is to promote student learning of the biochemical, molecular and cellular mechanisms underlying normal physiology and metabolism, thus providing a foundation for understanding disease processes. The course provides a foundation in cellular and molecular biology, including cell structure, cellular macromolecules, DNA, and RNA structure and function, protein synthesis, and regulation of gene expression, energetics, metabolism, regulation, organization and function of cellular organelles, flow of genetic information and the regulation of selected cell activities. The first semester will focus primarily on human molecular genetics. The second semester will primarily focus on metabolic pathways and inborn errors of metabolism. Critical thinking skills wi